2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carbaldehyde hydrate
Uracil-6-carboxaldehyde monohydrate
CAS: 36327-91-0;1052405-08-9
Molecular Formula: C5H4N2O3
2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carbaldehyde hydrate - Names and Identifiers
| Name | Uracil-6-carboxaldehyde monohydrate |
| Synonyms | OROTALALDEHYDE RARECHEM AH CK 0107 6-URACILCARBOXALDEHYDE 4-FORMYLURACIL MONOHYDRATE 6-FORMYL-URACIL MONOHYDRATE Uracil-6-carboxaldehyde monohydrate 2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carbaldehyde hydrate 4-Pyrimidinecarboxaldehyde, 1,2,3,6-tetrahydro-2,6-dioxo- (6CI,9CI) |
| CAS | 36327-91-0 1052405-08-9 |
| InChI | InChI=1/C5H4N2O3.H2O/c8-2-3-1-4(9)7-5(10)6-3;/h1-2H,(H2,6,7,9,10);1H2 |
2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carbaldehyde hydrate - Physico-chemical Properties
| Molecular Formula | C5H4N2O3 |
| Molar Mass | 140.1 |
| Density | 1.567±0.06 g/cm3 (20 ºC 760 Torr) |
| Melting Point | 340℃ (dec.) |
| Boling Point | 393.2°C at 760 mmHg |
| Flash Point | 191.6°C |
| Water Solubility | Slightly soluble in water. |
| Vapor Presure | 1.86E-07mmHg at 25°C |
| pKa | 5.63±0.10(Predicted) |
| Storage Condition | 2-8°C |
2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carbaldehyde hydrate - Risk and Safety
| Hazard Symbols | Xi - Irritant |
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. |
| Hazard Note | Irritant |
2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carbaldehyde hydrate - Introduction
Uracil-6-carboxaldehyde monohydrate(Uracil-6-carboxaldehyde monohydrate) is an organic compound with the chemical formula C6H6N2O3 · H2O. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: White crystalline powder or crystal.
-Melting point: about 185-190 ℃.
-Solubility: Soluble in water and organic solvents such as ethanol, methanol, etc.
Use:
- Uracil-6-carboxaldehyde monohydrate is an important intermediate in organic synthesis. It can be used to synthesize atorvastatin calcium (Atorvastatin calcium), which is a drug used to lower cholesterol.
-In addition, the compound can also be used in the synthesis of other drugs and compounds in organic synthesis.
Preparation Method:
- Uracil-6-carboxaldehyde monohydrate can be obtained by the reaction of uracil with 4-oxobutyric anhydride. The reaction generally needs to be carried out under basic conditions.
Safety Information:
- Uracil-6-carboxaldehyde monohydrate are general organic compounds in routine laboratory operations and can be handled in accordance with general safe operating procedures.
-Its toxicity is relatively low, but it is still necessary to avoid contact with skin and eyes, and avoid inhalation or intake during use.
-Wear appropriate personal protective equipment such as lab gloves, glasses, etc. when handling this compound.
-At the time of disposal, handle in accordance with local regulations and safe operating procedures.
Nature:
-Appearance: White crystalline powder or crystal.
-Melting point: about 185-190 ℃.
-Solubility: Soluble in water and organic solvents such as ethanol, methanol, etc.
Use:
- Uracil-6-carboxaldehyde monohydrate is an important intermediate in organic synthesis. It can be used to synthesize atorvastatin calcium (Atorvastatin calcium), which is a drug used to lower cholesterol.
-In addition, the compound can also be used in the synthesis of other drugs and compounds in organic synthesis.
Preparation Method:
- Uracil-6-carboxaldehyde monohydrate can be obtained by the reaction of uracil with 4-oxobutyric anhydride. The reaction generally needs to be carried out under basic conditions.
Safety Information:
- Uracil-6-carboxaldehyde monohydrate are general organic compounds in routine laboratory operations and can be handled in accordance with general safe operating procedures.
-Its toxicity is relatively low, but it is still necessary to avoid contact with skin and eyes, and avoid inhalation or intake during use.
-Wear appropriate personal protective equipment such as lab gloves, glasses, etc. when handling this compound.
-At the time of disposal, handle in accordance with local regulations and safe operating procedures.
Last Update：2024-04-09 02:00:45
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Product Name: Uracil Impurity 4 Visit Supplier Webpage Request for quotationCAS: 36327-91-0
Tel: 0714-3999186
Email: 2853786052@qq.com
Mobile: 86+15671228036
QQ: 2853786052
Wechat: 15671228036
Multiple Specifications
Product Name: 1,2,3,6-tetrahydro-2,6-dioxopyriMidin-4-carbaldehyde hydrate Visit Supplier Webpage Request for quotationCAS: 1052405-08-9
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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